Polyserine tract
WebJan 1, 2012 · By contrast, a polyserine tract was inactive. PolyQs acted from either an internal or a C-terminal position, thus ruling out a merely structural ‘linker’ effect. Finally, a … WebMar 10, 2011 · A recent advance reveals that RNA transcripts with expanded CAG repeats can be translated in the complete absence of a starting ATG, and this Repeat Associated Non-ATG translation (RAN-translation) occurs across expanded CAG repeats in all reading frames (CAG, AGC, and GCA) to produce homopolymeric proteins of long polyglutamine, …
Polyserine tract
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WebSep 1, 1998 · The data suggest that the polyserine tract of ICP4 provides an activity that is required for lytic infection in ganglia to progress to viral DNA synthesis and full lytic gene expression. ABSTRACT ICP4 of herpes simplex virus (HSV) is essential for productive infection due to its central role in the regulation of HSV transcription. WebDec 22, 2024 · Among the most interesting targets, we identified a choline/o-acetyltransferase domain-containing phosphoprotein that undergoes 5-IP 7-mediated phosphorylation events at a polyserine tract (Ser 578-580). We also identified a novel SPX domain-containing phosphoribosyltransferase [EC 2.7.6.1] herein termed as TcPRPPS4.
WebMar 30, 2015 · The polyserine tract in L7 is indicated by S's. (D) Side and top views of the β-barrel. Surface representations of L3, L4, L6, and L7 are shown using the same colors as in panels A and C. The polyserine tract in L7 is indicated with spikes. WebAug 29, 2011 · Vitellogenin (Vg) is an egg-yolk precursor protein in most oviparous species. In honeybee (Apis mellifera), the protein (AmVg) also affects social behavior and life-span plasticity. Despite its manifold functions, the AmVg molecule remains poorly understood. The subject of our structure-oriented AmVg study is its polyserine tract - a little ...
WebDec 22, 2024 · We prepared mutants with phosphomimetics (Ser 579 Asp) or full deletion of the polyserine tract (Ser 578-580) using the pET32/TcAc_CPI construct as template. Specific primers were designed following the instructions of the Q5 site-directed mutagenesis kit (NEB) (primers 25–28, Table S6 ) and mutations were verified by DNA sequencing … WebNov 1, 2006 · We have shown both +1 frameshift and +2 frameshift products (which may contain polyalanine or polyserine tracts, respectively) in human postmortem Huntington’s …
WebDespite its manifold functions, the AmVg molecule remains poorly understood. The subject of our structure-oriented AmVg study is its polyserine tract - a little-investigated repetitive …
Webregion of the GP60 gene encompassing the polyserine tract (variable numbers and forms of a repeating sequence of 3 nucleotides coding for the amino acid serine) and the hy-pervariable downstream region (5). We used a nested PCR protocol with primary PCR primers AL3531 and AL3535 and secondary primers AL3532 and AL3534. PCR prod- greater atlanta presbyteryWebPubMed flight we564WebMany human proteins have homopolymeric amino acid (HPAA) tracts, which are involved in protein-protein interactions and also have intrinsic polymerization properties. Polyglutamine or polyalanine expansions cause several neurodegenerative diseases. To examine the properties of HPAAs, we expressed 20 kinds of 30-residue HPAA fused to the C terminus … greater atlanta population 2021Weblength of the tract. By contrast, a polyserine tract was inactive. PolyQs acted from either an internal or a C-terminal position, thus ruling out a merely structural ‘ linker ’ effect. Finally, … greater atlanta rv show 2021WebWe have shown both +1 frameshift and +2 frameshift products (which may contain polyalanine or polyserine tracts, respectively) in human postmortem Huntington's disease … greater atlanta realtyWebAug 20, 1999 · The polyserine tract in the yeast H +-ATPase could form a potential phosphorylation site that might be involved in glucose activation of the enzyme. Glucose activation is believed to involve the C-terminus [24] and phosphorylation by casein kinase I enzyme at position Ser-507 [25] . greater atlanta urban leagueWebJan 9, 2024 · To validate the pull-down results, we endogenously tagged four protein candidates and immunopurified them. Among the most interesting targets, we identified a choline/o-acetyltransferase domain-containing phosphoprotein that undergoes 5-IP 7-mediated phosphorylation events at a polyserine tract (Ser 578-580). greater atlanta urology griffin ga